High Testosterone in Women: Causes, Symptoms and What to Do

High Testosterone in females: causes, symptoms, and more

High testosterone levels in women, though less common than in men, can have a significant impact on your health. When your body produces an excess amount of testosterone, it can lead to a variety of symptoms that affect both your physical appearance and your internal well-being. Understanding the causes of high testosterone is crucial to addressing any health concerns and restoring balance to your hormonal levels.

Testosterone, predominantly recognized as a male sex hormone, is also present in females, albeit in smaller quantities, exerting multifaceted effects on both genders6. In males, testosterone is integral to the development of secondary sexual characteristics, such as facial hair growth and deepening of the voice, as well as supporting reproductive function. Moreover, testes vs testis testosterone influences mood regulation, cognitive function, and bone density, contributing to psychological and skeletal health7,8. In females, while estrogen and progesterone are primary sex hormones, testosterone contributes to libido, energy levels, and overall vitality9. Thus, maintaining an optimal testosterone balance is crucial for sustaining physiological equilibrium and promoting general well-being. Maintaining an optimal testosterone balance is vital for muscle health, metabolic function, sexual health, mood regulation, and overall quality of life in both men and women10,11.

They were assured that their information would be kept anonymous and that the obtained results would only be used for the research. They are not medicines and are not intended to treat, diagnose, mitigate, prevent, or cure diseases. Be cautious about taking dietary supplements if you are pregnant or nursing.

The recommended treatment for high testosterone will depend on its underlying cause. This article will use the terms „male,“ „female,“ or both to refer to sex assigned at birth. If you’re struggling to catch Zzzs, try creating a relaxing bedtime routine and avoiding screens before bed. Additionally, you may want to talk to your doctor about any underlying sleep issues that could be causing you to toss and turn (think insomnia).

Aerobic exercises like jogging, swimming, and cycling can help maintain balanced hormone levels. Resistance training can also be beneficial but should be moderate to avoid stimulating testosterone production. High testosterone levels in women can have significant impacts on your health, particularly concerning your reproductive system and overall well-being. Anti-androgen medications like Spironolactone inhibit the production of testosterone. They may be prescribed in combination with oral contraceptives for better results.

We here report reduced serum testosterone levels in cis women with PBC compared with healthy age- and sex- matched controls. This is in accordance with reports from other autoimmune diseases, including SLE, MS, and RA, in which lower serum levels of testosterone have previously been reported (18, 19). Furthermore, testosterone serum levels negatively correlated with concentrations of proinflammatory cytokines IFN-γ and TNF, which are related to T cell activation (Figure 1). In addition to the observed correlations between testosterone levels and serum cytokine profiles, further analyses were performed to evaluate potential relationships with other clinical parameters (Supplemental Figure 3, A–C, and E). There was no correlation between serum testosterone levels and liver stiffness, age, or BMI, suggesting that the observed immune phenotypes are unlikely to be confounded by these variables.

Natural tips on how to lower testosterone in women can improve your hormonal health, but medications may be needed in the case of abnormally high testosterone levels. Around five million women(13) suffer from polycystic ovary syndrome (PCOS) in the US. PCOS is a hormonal disorder in women that causes excess production of androgens, including testosterone. Women may develop fertility problems, but PCOS can be managed with proper lifestyle changes and treatment. It is a hormonal condition that healthcare professionals believe has links to genetics. If you have high levels of testosterone, you may experience heavy, irregular periods or even missed periods.

Taken together, these data confirm a direct and AR-mediated effect of testosterone on murine CD4+ T cell differentiation and activation. To further validate these findings at the level of cytokine release, we performed ex vivo stimulation experiments with CD4+ T cells derived from WT and AR-deficient mice. These results align with the observed differentiation rates depicted in Figure 4F and further support the role of AR-mediated testosterone signaling in modulating murine T cell differentiation. Although women have lower testosterone concentrations, this hormone remains critical for various physiological functions, including muscle development, bone density maintenance, and overall metabolic health50(Clark et al., 2018).